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Wagner Syndrome

What is Wagner’s syndrome?

Wagner syndrome is a rare genetic disorder that results in progressive low vision . In people with Wagner syndrome, the retina (the translucent “screen” at the back of the eye) becomes thin and eventually becomes detached from the eye. In addition, the fluid in the eye, which normally has a gel-like substance, becomes thin and watery. Cataracts often occur as early as the age of 30, and low vision gets progressively worse from about this age. Not everyone has the disease to the same degree, but in most cases, retinal detachments occur and suffer from cataracts.

Wagner syndrome is an autosomal dominant disorder – people who have the condition pass it on to half of their children. People with the gene always develop symptoms. Thus, it is not possible to be a carrier without symptoms.

It is not known exactly how many people have this eye condition. Worldwide, there are at least 50 families in which this condition exists.

The realization that one’s vision is affected by this eye condition can be difficult to accept. Knowing that one is not the only one may provide support. There are many people in the same situation, some who have just been diagnosed themselves and some who have lived with it for years.

If one experiences low vision as a result then there are assistive devices available that can help with the tasks that one struggles with. These devices can provide support with tasks that one needs sight for and can help one continue to live a full and independent life.

What are the symptoms of Wagner’s syndrome?

Eye problems often include:

What can people expect from Wagner syndrome?

Most people with this eye condition will need multiple surgeries on the retina to repair its detachment. Treatments for cataracts are also often necessary. Because the gene responsible for the syndrome is known, there is hope that one day this condition can be prevented.